NCT06881030Not yet recruiting
Comparison of Different Acceleration Modes of Transcranial Magnetic Stimulation
Comparison of the Efficacy of Different Modes of Accelerated Transcranial Magnetic Stimulation in Treatment-resistant Depression
Source: ClinicalTrials.gov · Last updated 18 Mar 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
To compare the efficacy and safety of 6 times a day, 10 times a day acceleration mode and sham stimulation intervention for TRD, and to explore the antidepressant mechanism of accelerated mode, so as to provide a more simple and effective rapid treatment plan for TRD patients.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 45 (estimated)
- First submitted
- 10 Mar 2025
- Start date
- 25 Mar 2025
- Primary completion date
- 31 Aug 2025
- Lead sponsor
- First Affiliated Hospital of Zhejiang University
- Diseases
- Depression
- NCT number
- NCT06881030
What you commit to
- Study type: Interventional
- Planned participants: 45
- From 25 Mar 2025 to the primary completion date, 31 Aug 2025
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- 1\. Comorbidity with other mental disorders, including schizophrenia, mental retardation, substance dependence, etc.
- 2\. Suffering from serious or unstable physical diseases
- 3, pregnant, lactating women, women of childbearing age screening period urine HCG test results are positive
- 4\. Subjects with metal objects in the body or other contraindications to MRI scanning
- 5\. There are other conditions considered by the investigator to be inappropriate for participation in the clinical trial.
Who the study is looking for
- The current episode met the DSM-5 diagnostic criteria for major depression, without psychotic symptoms of the first or recurrent drug-free depressive subjects
- After a full course of treatment with two or more antidepressants, the patient had no response, and the level of treatment resistance was moderate to severe as assessed by the Maudsley staging method
- 3.24-item Hamilton depression Scale score ≥20
- 4.The age ranged from 18 to 45 years, both sexes
- 5.Right handed
- 6.Written informed consent was obtained and patients volunteered to participate in the study and be evaluated.
Age in the registry: 18 years to 45 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.