NCT06884228Active, not recruiting
Effects of Vibrating Mesh Nebulisation in Patients With COPD During Non-invasive Ventilation (VMN-NIV)
Source: ClinicalTrials.gov · Last updated 10 Jul 2026
Brief summary (registry, in English)
Assessment of the effects of vibrating mesh nebulisation versus jet nebulisation on the electrical activity of the muscles involved in breathing (neural respiratory drive), breathing mechanics (respiratory impedance measured by forced oscillation technique), respiratory flow, heart rate and rhythm, spirometry and breathlessness symptoms in patients with chronic obstructive pulmonary disease who require non-invasive ventilation.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 12 (estimated)
- First submitted
- 27 Feb 2025
- Start date
- 8 Apr 2025
- Primary completion date
- 12 Sept 2025
- Lead sponsor
- Guy's and St Thomas' NHS Foundation Trust
- Diseases
- COPD
- NCT number
- NCT06884228
What you commit to
- Study type: Interventional
- Planned participants: 12
- From 8 Apr 2025 to the primary completion date, 12 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe, non-respiratory organ dysfunction including, but not limited to:
- Congestive cardiac failure
- Significant cardiovascular disease
- End-stage malignancy
- End-stage renal failure
- Severe cognitive impairment
Other
- Acute pulmonary pathology requiring emergency treatment including, but not limited to:
- Pneumonia
- Pneumothorax
- Pulmonary embolism
- Psychosocial factors that would preclude completion of the study protocol
Who the study is looking for
- Patients with COPD receiving home non-invasive ventilation for chronic respiratory failure under the Lane Fox Respiratory Service at Guy's and St Thomas' NHS Foundation Trust
- Tolerating home non-invasive ventilation for at least 4 hours/24 hours
- Aged 18-80 years old
- Able to communicate symptom burden to the research team
- Able to give informed consent for participation in the study
- Clinical stability, with no acute exacerbations of COPD for 2 weeks prior to enrolment
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lane Fox Unit, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.