NCT06888440Completed
Zinc Stents for the Treatment of Gingivitis
Clinical Effects of Zinc-containing Stents on Gingivitis: a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 21 Mar 2025
Brief summary (registry, in English)
Background This study investigates the effects of zinc-containing stents on gingival inflammation, bleeding, and plaque regrowth in gingivitis patients. Methods A randomized, double-blind, placebo-controlled study was conducted at Çukurova University, enrolling 42 systemically healthy gingivitis patients aged 18-30. Participants were assigned to either a test group (zinc-containing stents) or a control group (placebo stents) and instructed to wear their stents for at least 12 hours daily for four weeks. Clinical measurements, including Gingival Index (GI), Plaque Index (PI), and Bleeding on Probing (BOP), were assessed at baseline, and at the 2nd, 4th, and 8th weeks. Statistical analysis was performed using IBM SPSS and RStudio.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 42 (actual)
- First submitted
- 14 Mar 2025
- Start date
- 1 Oct 2023
- Primary completion date
- 1 Apr 2024
- Lead sponsor
- Cukurova University
- NCT number
- NCT06888440
What you commit to
- Study type: Interventional
- Participants enrolled: 42
- From 1 Oct 2023 to the primary completion date, 1 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of antibiotics or anti-inflammatory medication within the preceding 6 months,
Other illness
- Subjects with a history of allergies to Zinc,
- The presence of hematologic disorders or any other systemic illness,
- History of periodontal therapy,
Other
- Pocket probing depth (PPD) of ≥4 mm,
- Interdental clinical attachment loss (CAL) detectable at ≥2 nonadjacent teeth or displaying buccal/oral CAL ≥3 mm coupled with PD ≥3 mm
- Pregnancy and breastfeeding,
- Current orthodontic treatment,
- Smoking.
Who the study is looking for
- Presence of plaque-induced gingivitis \[bleeding on gentle probing at \>30% of sites examined and a gingival index (GI) of at least 1 at \>60% of sites examined\],
- Plaque index (PI) of ≥ 2 according to the modified Quigley\&Hein index,
- 18-30 years old,
- At least 20 natural teeth,
- Systemically healthy.
Age in the registry: 18 years to 30 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cukurova University Faculty of Dentistry Coordinator of this site? Confirm its status | Adana | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.