NCT06892561Active, not recruiting
Phase-Aligned Atrial Fibrillation Mapping
Atrial Fibrillation Mapping Using Phase-Aligned Spectral Filtering for Decomposing Spatiotemporal Dynamics
Source: ClinicalTrials.gov · Last updated 1 Jul 2026
Brief summary (registry, in English)
Cardiac arrhythmia in the upper chamber of the heart (atrial fibrillation) can be cured by burning. Physicians burn very small pieces of abnormal tissue. It is important to know where to burn. The investigators propose a new way to find out where to burn. The investigators will use a new way to analyze electrical signals inside the heart and build a new electric map. The study may lead to the development of new technology. In the future, novel technology may increase the success rate and the number of cured atrial fibrillation patients. This study is a retrospective study of data collected during routine clinical care: atrial fibrillation ablations. The investigators will compare intracardiac electrograms and atrial activation maps in patients who had successful ablation outcomes (no recurrence within 1 year) and those who experienced a recurrence of arrhythmia within 1 year after the procedure.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 336 (actual)
- First submitted
- 19 Mar 2025
- Start date
- 16 Aug 2023
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Larisa Tereshchenko, MD, PhD
- Diseases
- Atrial fibrillation
- NCT number
- NCT06892561
What you commit to
- Study type: Observational
- Participants enrolled: 336
- From 16 Aug 2023 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Familial AF, AF as a syndrome in rare diseases (cardiomyopathies / WPW/ channelopathies).
Other
- Missing data of exposure (AF ablation map), outcome (definition of cases and controls), or covariates
Who the study is looking for
- Records of patients with persistent AF who underwent pulmonary vein isolation (PVI) with any additional AF ablation strategy with available stored digital AF mapping data. Persistent AF is defined as AF lasting more than 7 days.
- One/First AF ablation procedure (no prior atrial ablation procedures)
- Documented complete pulmonary vein isolation at the end of the ablation
- Available uniform, high-quality (as described below) clinical data required to detect AF recurrence during ≥ 1 year after ablation, and/or ECG monitoring (implantable loop recording or repeated long-term ECG monitoring via ECG patch or similar)
Age in the registry: 18 years to 89 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.