NCT06894680Completed
Integrating Depression Care Into HIV Services for Older People With HIV Using a Stepped Care, Task-Sharing Approach.
The Adaptation of a Stepped Care, Task-sharing Approach for Integrating Depression Care for Older People Living With HIV (PLHIV) Into HIV Treatment and Support Services in Ibadan, Nigeria.
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
Depression levels will be compared using PHQ-9 in the Treatment as Usual arm(TAU) VS intervention arm to see if the stepped care intervention is effective in treating depression. The main questions it aims to answer are: * Needs assessment of stepped-care integration versus usual care for treating depression in older adults living with HIV? * How effective will the stepped care task-sharing (SCT) model in reducing depressive symptoms and improving HIV treatment outcomes in older PLHIV in Nigeria? Participants who screen positive for depression PHQ-9 ≥10 will be randomized into 2 arms for treatment using a systemized ballot system: TAU arm and Intervention arm. TAU arm will receive current treatment available for depression at the HIV center. Intervention arm will receive the stepped-care intervention in stages based on their symptom severity. Follow-up assessments at (6 weeks, 3months, 6 months, 9 months and 12 months) will be conducted by assessors who would be blinded to the different groups (TAU arm VS intervention arm).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 100 (actual)
- First submitted
- 18 Mar 2025
- Start date
- 24 Mar 2025
- Primary completion date
- 28 Apr 2025
- Lead sponsor
- Royal Society of Tropical Medicine and Hygiene
- Diseases
- HIV
- NCT number
- NCT06894680
What you commit to
- Study type: Interventional
- Participants enrolled: 100
- From 24 Mar 2025 to the primary completion date, 28 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- • Older PLHIV will be assessed for the imminent risk of suicide and if there is an high risk, participant will be excluded.
- Older PLHIV with severe cognitive impairment or diagnosed dementia that limits their ability to provide informed consent or complete study visits will be excluded.
- Participants with comorbidities that can preclude the use of sertraline should be excluded.
Who the study is looking for
- Consenting individuals living with HIV
- People living with HIV who are 50 years and above (PLHIV aged ≥50 years)
- Those with a score of ≥10 on the 9-item patient-health questionnaire (PHQ-9).
Age in the registry: 50 years to 100 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institute of Infectious Diseases Coordinator of this site? Confirm its status | Ibadan | Nigeria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.