NCT06896578Not yet recruiting
Latitude - Lateral Lymph Node Attitude Study
Lateral Lymph Nodes in Rectal Cancer Attitude Study
Source: ClinicalTrials.gov · Last updated 8 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Patients with advanced rectal cancer can sometimes have suspected tumour affected lymph nodes outside the standard operating field. These patients often receive preoperative treatment before surgery. There is a lack of consensus on what to do if there is remaining suspicion of tumour affected lymph nodes after the preoperative treatment. Removal of the lymph nodes using a broader surgical field with dissection of the lateral side-wall is often suggested, but the oncologic outcome is uncertain, and so is the patient reported outcome in terms of side effects. This study aims to study the surgical treatment of tumour affected lateral lymph nodes to understand what lymph nodes require removal, and what effect that will have on oncologic outcome and the patient's function and QoL.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 1000 (estimated)
- First submitted
- 9 Jan 2025
- Start date
- 15 Sept 2025
- Primary completion date
- 1 Feb 2029
- Lead sponsor
- Sahlgrenska University Hospital
- Diseases
- Colorectal cancer
- NCT number
- NCT06896578
What you commit to
- Study type: Interventional
- Planned participants: 1000
- From 15 Sept 2025 to the primary completion date, 1 Feb 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Not biopsy confirmed rectal cancer (adenocarcinoma)
- Recurrent rectal cancer
Age
- Age below 18
Other
- Participation in other trials in conflict with the protocol and end-points of the Latitude study
- No informed consent
Who the study is looking for
- 18 years or older
- written informed consent
- adenocarcinoma verified tumour below ≤ 8 cm from anal verge measured by rectoscopy and/or MRI
- clinical tumor (cT) stage cT3, cT4a or cT4b on MRI or
- adenocarcinoma verified tumour at any height ≤ 15 cm from anal verge measured by rectoscopy and/or MRI regardless of T/N stage with visible lateral lymph node (according to definition 2.4.2) on pre-therapeutic MRI or PET-CT
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dept. of Surgery, Sahlgrenska University Hospital/Ostra Coordinator of this site? Confirm its status | Gothenburg | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.