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NCT06896903Recruiting

Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing

Source: ClinicalTrials.gov · Last updated 5 May 2026

Brief summary (registry, in English)

This single-arm, multi-center, prospective study will assess the coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and determinants thereof (transit time, Pa, Pd) in patients before and after intracoronary nitroglycerine.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
50 (estimated)
First submitted
20 Mar 2025
Start date
21 May 2025
Primary completion date
1 May 2027
Lead sponsor
Baylor Research Institute
NCT number
NCT06896903

What you commit to

  • Study type: Interventional
  • Planned participants: 50
  • From 21 May 2025 to the primary completion date, 1 May 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous percutaneous interventions within the coronaries
  • Current use (within 48 hours) of long-acting nitrate therapies
  • Current use (within 48 hours) of PDE-5 inhibitors (sildenafil, tadalafil)

Other illness

  • Existing coronary artery disease
  • Any other condition or co-morbidity which, in the opinion of the investigator or operator, may pose a significant hazard to the subject if he or she is enrolled in the study.

Other

  • Children below 18 years, prisoners, pregnant people and patients who are unable to provide consent are excluded.

Who the study is looking for

  • Aged 18 or older
  • Patient being evaluated for ANOCA or INOCA
  • Clinical suspicion for angina
  • Patient should be able to comply with the protocol.
  • Provide written informed consent before study participation.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Baylor Scott & White The Heart Hospital - Plano
Coordinator of this site? Confirm its status
PlanoUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.