NCT06899776Active, not recruiting
Assessing Chest Pain Using Point-of-Care High-Sensitivity Troponin I in the Emergency Department
Source: ClinicalTrials.gov · Last updated 29 Jul 2026
Brief summary (registry, in English)
The goal of this proposal is to improve the quality and value of care for patients with acute chest pain by investigating the potential impact of point-of-care (POC) high sensitivity cardiac troponin (hs-cTn) testing in the Emergency Department (ED) and exploring how best to integrate POC hs-cTnl into ED risk stratification workflows. The study hypothesizes that the Abbott i-STAT POC hs-cTnI assay will decrease time-to-result (TTR) and ED length of stay (LOS), while increasing ED revenue for patients with acute chest pain compared to a strategy of central laboratory hs-cTnI testing.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 5 Mar 2025
- Start date
- 7 Feb 2025
- Primary completion date
- 15 Sept 2025
- Lead sponsor
- Wake Forest University Health Sciences
- Diseases
- Coronary artery disease
- NCT number
- NCT06899776
What you commit to
- Study type: Observational
- Planned participants: 600
- From 7 Feb 2025 to the primary completion date, 15 Sept 2025
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior enrollment
Other illness
- ST-segment elevation myocardial infarction (STEMI) Activation
Lab values
- Central laboratory hs-cTn testing resulted or in process (\>5 minutes) prior to study accrual
Other
- Unstable vitals signs: symptomatic hypotension at the time of enrollment (systolic \< 90 mm Hg), tachycardia (HR\>120), bradycardia (HR\<40), and hypoxemia (\<90% pulse-oximetry on room air or normal home oxygen flow rate)
- Terminal diagnosis with life expectancy less than 6 months
Who the study is looking for
- Age greater than or equal to18 years
- Symptoms suggestive of acute coronary syndrome:
- Acute chest, epigastric, neck, jaw or arm pain or discomfort or pressure without apparent non-cardiac source
- Shortness of breath, nausea, vomiting, fatigue/malaise, or
- Other equivalent discomfort suggestive of an myocardial infarction (MI)
- Electrocardiogram (ECG) ordered as part of standard of care
- At least one troponin collected as standard of care
- Study specific blood sample collected within ± 5 minutes of clinical draw
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Carolinas Medical Center Coordinator of this site? Confirm its status | Charlotte | United States | Unknown status |
| High Point Medical Center Coordinator of this site? Confirm its status | High Point | United States | Unknown status |
| Wake Forest School of Medicine Coordinator of this site? Confirm its status | Winston-Salem | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.