NCT06902701Not yet recruiting
Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal Neoplasia
Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal Neoplasia: A Multicenter Prospective Observational Cohort Study
Source: ClinicalTrials.gov · Last updated 24 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This prospective observational cohort study aims to compare the clinical and procedural outcomes of Endoscopic Submucosal Dissection (ESD) and Transanal Minimally Invasive Surgery (TAMIS) for the treatment of early-stage rectal neoplasia. The study will evaluate recurrence rates, en bloc resection rates, R0 resection rates, procedure time, complication rates, and length of hospital stay over a 1-year follow-up period. Data will be collected from patients treated at multiple centers with expertise in ESD and TAMIS.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 156 (estimated)
- First submitted
- 16 Mar 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- Turkish Society of Colon and Rectal Surgery
- Diseases
- Colorectal cancer
- NCT number
- NCT06902701
What you commit to
- Study type: Observational
- Planned participants: 156
- From 1 Jul 2025 to the primary completion date, 1 Jun 2027
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous attempt at endoscopic resection
- Previous rectal surgery
- Previous pelvic radiation therapy
Other illness
- Inflammatory bowel diseases (Crohn's disease, Ulcerative colitis)
Other
- Evidence of lymph node involvement, T2 rectal tumors, or distant metastasis on preoperative imaging modalities (MRI, ERUS, CT)
Who the study is looking for
- Adult patients (\>18 years)
- Non-pedunculated (sessile) lesions larger than 2 cm.
- Lesions located within 15 cm from the anal verge confirmed by sigmoidoscopy or magnetic resonance imaging (MRI)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Private Office Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
| Memorial Sisli Hospital Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
| Baskent University Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
| Acibadem Kent Hospital Coordinator of this site? Confirm its status | Izmir | Turkey (Türkiye) | Unknown status |
| Dokuz Eylul University Coordinator of this site? Confirm its status | Izmir | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.