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NCT06904287RecruitingPhase 3

Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines

Evaluating the Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines in the Emergency Department

Source: ClinicalTrials.gov · Last updated 22 Jan 2026

Brief summary (registry, in English)

The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.

Status (registry)
Recruiting
Phase (registry)
Phase 3
Study type
Interventional
Enrollment
100 (estimated)
First submitted
24 Mar 2025
Start date
16 Dec 2025
Primary completion date
Jun 2027
Lead sponsor
Wake Forest University Health Sciences
Diseases
Migraine
NCT number
NCT06904287

What you commit to

  • Study type: Interventional · Phase 3
  • Planned participants: 100
  • From 16 Dec 2025 to the primary completion date, Jun 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Consumption of study drug within 48 hours prior to enrollment
  • Previously enrolled in this trial during a different patient encounter

Other illness

  • Allergy or sensitivity to study drug
  • Stated history of renal insufficiency
  • Documented history of myasthenia gravis

Other

  • Pregnancy defined as a positive urine HCG

Who the study is looking for

  • Age ≥ 18 years or older
  • Able to provide informed consent
  • English speaking
  • Primary diagnosis of migraine. Patient with a previous diagnosis of migraine, who experience headaches with typical migraine features (e.g at least 2-3 of the following: recurrent, unilateral, pounding or throbbing in nature, associated with nausea), AND with a clinical exclusion of migraine mimics

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Advocate Christ Medical Center Emergency Department
Coordinator of this site? Confirm its status
Oak LawnUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.

Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines (NCT06904287) – Frontlight Research