NCT06905028Active, not recruiting
Exploratory Clinical Study on Fasting in Psoriasis and Psoriatic Arthritis (RiseFast)
The Impact of Fasting on Disease Activity and the Gut Microbiota in Patients With Psoriasis and Psoriatic Arthritis - the RiseFast Pilot Study
Source: ClinicalTrials.gov · Last updated 8 Jun 2026
Brief summary (registry, in English)
The RiseFast pilot study will investigate the clinical, metabolic and immunological effects of fasting and plant-based diet (PBD) on patients with psoriasis (PsO) and psoriatic arthritis (PsA) on their gut microbiota. The project will combine clinical assessments, cytometric profiling, and gut microbiota analysis to explore the relationship between fasting, a plant-based diet, and psoriatic disease. The study includes a 7-day fasting period followed by 11 weeks of PBD, with the goal of improving disease activity, quality of life, and understanding the role of gut microbiota in these conditions. This approach could lead to low-cost, accessible therapeutic options with minimal side effects.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 25 Mar 2025
- Start date
- 4 Apr 2025
- Primary completion date
- 1 Oct 2026
- Lead sponsor
- Charite University, Berlin, Germany
- Diseases
- Psoriasis, Psoriatic arthritis
- NCT number
- NCT06905028
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 4 Apr 2025 to the primary completion date, 1 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- eating disorder in the last 5 years
Lab values
- severe internal diseases (e.g. renal insufficiency with creatinine \> 2mg/dl)
Other
- Pregnancy or breastfeeding
- underweight (BMI ≤18,5)
- current practice of vegan diet or fasting within the past 6 months
- use of antibiotics within the past 3 months
Who the study is looking for
- Active plaque psoriasis (PASI ≥3) or Psoriatic Arthritis fulfilling the Classification Criteria for Psoriatic Arthritis (CASPAR) and not meeting MDA criteria
- on stable baseline psoriatic treatment for 12 weeks before enrollment
- ≥ 18 years old
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Charité - Universitätsmedizin Berlin, Psoriasis-Forschungs- und BehandlungsCentrum Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.