NCT06908174Recruiting
Differences in Prosocial Behaviors and Related Brain Networks in Children With Autism and Typical Development
Source: ClinicalTrials.gov · Last updated 29 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this observational study is to compare the brain functional network between children with autism and typical development, using magnetic resonance imaging (MRI), electroencephalogram/event-related potentials(EEG/ERPs) and functional Near Infrared Spectrum(fNIRs). The main questions it aims to answer are as follows: 1. What are the differences of the functional brain network between autism and TD children? 2. What are the differences of the brain activity in response to special social stimulus between autism and TD children? Participants will receive developmental/intelligence assessments (Griffiths Mental Developmental Scales/Wechsler Preschool and Primary Scale of Intelligence-IV/Wechsler Intelligence Scale for Children-IV for children of different ages), social assessments(Autism Diagnostic Observation Schedule-2nd Edition/Social Communication Questionnaire), EEG/ERPs and fNIRs in resting and task states, and head MRI in natural sleeping state(without sedative).
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 19 Feb 2025
- Start date
- 7 Apr 2025
- Primary completion date
- 1 Jul 2029
- Lead sponsor
- Children's Hospital of Fudan University
- Diseases
- Autism
- NCT number
- NCT06908174
What you commit to
- Study type: Observational
- Planned participants: 300
- From 7 Apr 2025 to the primary completion date, 1 Jul 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Rett Syndrome, Fragile X Syndrome, Angelman Syndrome, Prader-Willi Syndrome, tuberous sclerosis, and other syndromes caused by known genetic defects or inherited metabolic diseases;
- Children with brain injuries, specific chronic or congenital diseases.
- Children with brain injuries, specific chronic or congenital diseases.
Age
- The gestational age is less than 37 weeks, or the birth weight is lower than 2500g.
- The gestational age is less than 37 weeks, or the birth weight is lower than 2500g.
Other
- Children cannot receive the head MRI examination.
- Control group:
- Children cannot receive the head MRI examination.
Who the study is looking for
- Children diagnosed with ASD according to a clinical judgement based on the criteria of ASD in DSM-5 and further confirmed with ADOS-2;
- Ages 2-17 years;
- Parents/caregivers understand the content of the study and agree to participate in.
- Healthy children age between 2 to 17 years.
- Children without the family history of ASD or other neurodevelopmental/mental diseases.
- Parents/caregivers understand the content of the study and agree to participate in.
Criteria the registry did not label
- Case group:
Age in the registry: 2 years to 17 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital Of Fudan University Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.