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NCT06911229Recruiting

Neurophysiology of Locomotor Adaptation and Freezing of Gait in Parkinson's Disease

Source: ClinicalTrials.gov · Last updated 15 Jul 2026

Brief summary (registry, in English)

Locomotor adaptation will be studied using an established split-belt treadmill paradigm, consisting of baseline (1:1 speed ratio), split-belt adaptation (2:1) and post-adaptation (1:1) walking. Split-belt walking will be performed under DBS ON and DBS OFF conditions, while off-medication.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
28 Mar 2025
Start date
1 Oct 2025
Primary completion date
31 Jul 2027
Lead sponsor
University of Florida
NCT number
NCT06911229

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From 1 Oct 2025 to the primary completion date, 31 Jul 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • other previous neurological surgery;

Other illness

  • suspicion of other neurologic diagnoses such as atypical parkinsonism, or Alzheimer's disease.

Who the study is looking for

  • consensus diagnosis of idiopathic PD by fellowship trained movement disorders neurologists at the Normal Fixel Institute of Neurological Diseases;
  • chronically stable DBS, defined as having had DBS for at least 6 months in duration with optimized DBS settings;
  • Age between 18 - 80 years old per the FDA data sheet for PD DBS;
  • no dementia according to the clinical diagnostic criteria for PD dementia;
  • ambulatory without the use of walking aids, or another person's assistance.

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Florida
Coordinator of this site? Confirm its status
GainesvilleUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.