Acupuncture for People Experiencing Period Loss Due to Chemotherapy

Prior treatment

• Had been pregnant or lactating within 3 months prior to enrollment
• Ongoing or planned radiation or surgery within 4 months from randomization
• Had been or will be receiving ovarian suppression medicine, such as leuprolide (Lupron) and goserelin (Zoladex), or hormonal contraception drugs within 3 months of enrollment or during the study period

Other illness

• History of hysterectomy or bilateral oophorectomy

Other

• Use of acupuncture for menses recovery within 3 months of enrollment

• English speaking woman between the ages of 15 and 40
• History of stage I, II, or III cancer OR stage IV or unstaged hematologic malignancy (e.g. lymphoma, leukemia, myeloma) that is stable, as assessed by care team
• Premenopausal status with regular menstruation at the time of diagnosis by patient report
• Completed cytotoxic chemotherapy within the past year
• Premenopausal status with regular menstruation at the time of diagnosis by patient report for females ages 18 or older
• Report cessation of menses during or after chemotherapy and have not experienced menses recovery at the time of enrollment.
• Have reached menarche prior to therapy or during therapy for females between 15 and 17 years old
• Patient meets at least one of the following:
• Reports cessation of menses during or after chemotherapy and have not experienced menses recovery at the time of enrollment and has been without menses for at least 3 months 64 following the completion of cytotoxic chemotherapy; OR
• Is receiving ovarian suppression therapy (e.g., leuprolide \[Lupron\] or goserelin \[Zoladex\]) or hormonal contraceptive drugs, regardless of menstrual status, and report persistent (≥3 months), moderate-to- severe menopause-related symptoms, defined as a score of ≥4 on a 0-10 scale for at least one MENQOL item during eligibility screening.
• Willing to adhere to all study-related procedures, including randomization to one of the two possible arms: acupuncture and WLC