NCT06916715Active, not recruiting
MR Elastography in Intracranial Lesions: Feasibility & Accuracy
Feasibility and Diagnostic Accuracy of Magnetic Resonance Elastography in Intracranial Space-Occupying Lesions
Source: ClinicalTrials.gov · Last updated 30 Apr 2026
Brief summary (registry, in English)
Brain tumors, despite their relatively low incidence among cancers, are associated with high morbidity and mortality due to the brain's complexity. Biopsy, the gold standard for tumor grading, is limited by invasiveness, costs, and sampling issues. Conventional MR imaging lacks sensitivity to differentiating tumor grades, while magnetic resonance elastography (MRE) offers non-invasive assessment potential. This retrospective study reviewed MRE data from 626 brain tumor patients (May 2017-September 2025) to evaluate MRE's diagnostic performance, success rate in tumor grading, and clinical reliability, aiming to advance its role in non-invasive brain tumor assessment.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 626 (actual)
- First submitted
- 31 Mar 2025
- Start date
- 9 May 2017
- Primary completion date
- 25 Sept 2026
- Lead sponsor
- Shengjing Hospital
- Diseases
- Childhood cancers
- NCT number
- NCT06916715
What you commit to
- Study type: Observational
- Participants enrolled: 626
- From 9 May 2017 to the primary completion date, 25 Sept 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Tumor diameter \> 2 cm
- MR elastography performed within one week before surgery
- Patients were excluded if they had:
- incomplete MRI or MRE data
- A history of brain trauma, brain tumors, or surgery
- Received chemotherapy, radiotherapy, or hormone therapy for any reason before surgery
- Tumors that could not be assigned grades according to the fifth edition of the WHO Classification of CNS (WHO CNS5)
- MRE examinations with suboptimal wave image quality (e.g., motion artifacts or inadequate wave amplitude)
Age in the registry: 7 years to 83 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shengjing Hospital Coordinator of this site? Confirm its status | Shenyang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.