NCT06918418CompletedPhase 4
A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children
Comparison of Salbutamol Alone and Salbutamol in Combination With Ipratropium Bromide in Treatment of Acute Asthma in Children
Source: ClinicalTrials.gov · Last updated 9 Apr 2025
Brief summary (registry, in English)
The goal of this clinical trial was to determine if adding ipratropium bromide to salbutamol improves asthma treatment in children. The main question this study aimed to answer was: Does combining ipratropium with salbutamol improve asthma symptoms more effectively than salbutamol alone? Researchers compared salbutamol alone to a combination of salbutamol and ipratropium in children with acute asthma. Participants: (i) Received either salbutamol alone or salbutamol with ipratropium via nebulization for 4 hours (ii) Had their asthma symptoms assessed before and after treatment (iii) Were discharged with continued treatment and counseling if stable This study was conducted in the Department of Pediatric Medicine, Children's Hospital Multan, over six months. A total of 60 children with acute asthma were included.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 2 Apr 2025
- Start date
- 1 Jan 2024
- Primary completion date
- 30 Jun 2024
- Lead sponsor
- Children's Hospital and Institute of Child Health, Multan
- Diseases
- Asthma
- NCT number
- NCT06918418
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 60
- From 1 Jan 2024 to the primary completion date, 30 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Children with known pulmonary and/or cardiac congenital malformations
- Altered mental status on presentation with imminent respiratory failure (pulmonary asthma score ≥ 10, cases needing PICU care)
Other
- Bronchopulmonary dysplasia
- Cystic fibrosis
- Post infectious bronchiolitis obliterans
Who the study is looking for
- Children with acute asthma exacerbation (presenting with wheeze, labored breathing with ronchi audible on auscultation)
- Within 12 hours of symptom onset
Age in the registry: 2 years to 15 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Hospital and institute of Child Health Coordinator of this site? Confirm its status | Multan | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.