NCT06919614RecruitingPhase 3
STI Testing to Enhance PrEP Use in Pregnancy
Improving PrEP Outcomes Among Pregnant Women in Botswana With an Integrated STI Testing and PrEP Delivery Model
Source: ClinicalTrials.gov · Last updated 11 Jun 2026
Brief summary (registry, in English)
The investigators are conducting a study in Botswana to see if offering STI testing along with expanded HIV prevention options (PrEP) helps more pregnant women start and continue using PrEP during and after pregnancy. Pregnant women (n=600) seeking antenatal care in Botswana will be enrolled and randomly assigned to receive the standard of care (standard STI assessment with no STI testing) versus STI testing for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis during pregnancy and postpartum. The investigators' hypothesis is that providing STI testing alongside PrEP offer will encourage more women to start and continue using PrEP.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 600 (estimated)
- First submitted
- 2 Apr 2025
- Start date
- 18 Jun 2025
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- Botswana Harvard AIDS Institute Partnership
- Diseases
- HIV
- NCT number
- NCT06919614
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 600
- From 18 Jun 2025 to the primary completion date, 31 Aug 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently using PrEP
Other illness
- Living with HIV
Other
- Male gender
- Not pregnant
- Not planning to remain in the city/town of enrolment until 9 months post-delivery
- Not planning to receive antenatal and postnatal care in the city/town to enrolment
- Not able or willing to provide informed consent for participation
Who the study is looking for
- Pregnant and seeking antenatal care
- Self-identifying as a cis-gender woman
- Living without HIV
- Not currently using PrEP
- Planning to remain in the city/town of enrolment until 9 months post-delivery.
- Planning to receive antenatal and postnatal care in the city/town of enrolment.
- Willing and able to provide informed consent
Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| DHMT Clinics Coordinator of this site? Confirm its status | Gaborone | Botswana | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.