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NCT06923618Recruiting

Cancer of the Lung And SeneScencE - Prospective Cohort 1

Identification of Aging Biomarkers for Better Tailoring of Cancer Treatment in Older Patients With Lung Cancer: a Multicenter Clinico-biological Cohort Study

Source: ClinicalTrials.gov · Last updated 15 Dec 2025

Brief summary (registry, in English)

The main objective is to identify and assess the predictive value of ageing and senescence biomarkers (methylome, telomeres, inflammageing) and senescent cells in tissues to improve prognosis assessment older patients with locally or locally-advanced Non-Small Cell Lung Cancer (NSCLC).

Status (registry)
Recruiting
Study type
Interventional
Enrollment
385 (estimated)
First submitted
17 Feb 2025
Start date
9 Jul 2025
Primary completion date
Jul 2028
Lead sponsor
Assistance Publique - Hôpitaux de Paris
Diseases
Lung cancer
NCT number
NCT06923618

What you commit to

  • Study type: Interventional
  • Planned participants: 385
  • From 9 Jul 2025 to the primary completion date, Jul 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Synchronous cancer (histologically proven or strongly suspected non-lung cancer in the 6 months prior to inclusion (excluding basal cell cancer and prostate cancer with local treatment (radiotherapy or surgery) or active surveillance without systemic treatment (chemotherapy, hormone therapy)).

Other illness

  • Subject unable to understand the purpose and conditions of the study and unable to give consent

Other

  • Subject deprived of liberty by judicial or administrative decision or patient under guardianship

Who the study is looking for

  • Patients 70 years and over
  • Local or locally advanced (Clinic stage I-IIIA) NSCLC (clinically (or radiologically) suspected or histologically proven)
  • Surgical Curative Intent
  • Signed informed Consent (or signed by the curator or tutorship)
  • Affiliated to social security administrative care service

Age in the registry: 70 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Henri Mondor Hospital
Coordinator of this site? Confirm its status
CréteilFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.