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NCT06926166Recruiting

Human Genes and Microbiota in Early Life

Human Genes and Microbiota in Early Life (HuGME)

Source: ClinicalTrials.gov · Last updated 16 Sept 2026

Brief summary (registry, in English)

The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life and their interaction with the host on maternal-offspring health consequences in later life in the born in Guangzhou cohort study in China. Identification of the effect of microbiota in early life, as well as environmental factors and microbe-host interaction, will lead to a better understanding of disease pathogenesis and provide a foundation for targeted mechanistic investigation into the consequences of microbial-host crosstalk for long-term health. It also can result in new strategies to predict and prevent diseases in later life.

Status (registry)
Recruiting
Study type
Observational
Enrollment
20000 (estimated)
First submitted
26 Mar 2025
Start date
1 Apr 2019
Primary completion date
31 Dec 2038
Lead sponsor
Guangzhou Women and Children's Medical Center
NCT number
NCT06926166

What you commit to

  • Study type: Observational
  • Planned participants: 20000
  • From 1 Apr 2019 to the primary completion date, 31 Dec 2038
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Refuses to have blood and stool samples stored at Born in Guangzhou cohort study Biobank.

Who the study is looking for

  • Pregnant women with \< 20 weeks of gestation Pregnant women intended to eventually deliver in Guangzhou Women and Children's medical center Permanent residengts of families intended to remain in Guangzhou with their child for ≥3 years

Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Guangzhou Women and Children's Medical Center, China
Coordinator of this site? Confirm its status
GuangzhouChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.