NCT06927973Completed
Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction
Source: ClinicalTrials.gov · Last updated 23 Dec 2025
Brief summary (registry, in English)
The purpose of this study is to find out if additional images taken during a stress echocardiogram study and risk score calculation will help the doctor determine if shortness of breath or chest pain are caused by stiff heart (heart failure with preserved ejection fraction or HFpEF).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 7 Apr 2025
- Start date
- 30 May 2025
- Primary completion date
- 19 Dec 2025
- Lead sponsor
- Duke University
- Diseases
- Heart failure
- NCT number
- NCT06927973
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 30 May 2025 to the primary completion date, 19 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known history of HFpEF
- History of hypertrophic cardiomyopathy, amyloidosis, or pulmonary arterial hypertension, severe right ventricular dysfunction and severe valvular disease based on chart review or baseline echo study
- History of organ transplant (heart, kidney, liver, lungs)
- Severe pulmonary disease requiring ambulatory oxygen therapy
- End-stage renal disease requiring long-term renal replacement therapy
- Decompensated liver disease
- Conditions that prevent accurate assessment of E/e' ratio (mitral prosthetic valve, severe mitral annular calcification)
Lab values
- LVEF \<50% on baseline echo study
Other
- Plan to use echo contrast agent during stress study (i.e. contrast agent needed for baseline study)
- Patients from outside Duke health system with no plan for long-term care at Duke
Who the study is looking for
- Clinically indicated exercise stress echo for the evaluation of exertional dyspnea or chest pain
- Age ≥50 years
Age in the registry: 50 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Duke University Medical Center Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.