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NCT06928675Recruiting

Cell-free DNA in Acute Stroke

CANTO - Cell-free DNA in Acute Stroke

Source: ClinicalTrials.gov · Last updated 15 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Cell-free DNA (cfDNA) is an important pro-inflammatory and prothrombotic mediator. With this study the investigators aim to gain new insights into the role of cfDNA in stroke and to perform a combined analysis of cfDNA in the hyperacute phase of the disease using blood and thrombus analyses. The main objectives are to analyse cfDNA in different stroke etiologies, to investigate the relationship between cfDNA and important procedural factors such as secondary embolisation and reperfusion outcomes, to analyse the correlation between blood and thrombus content of cfDNA and to investigate the specific source of cfDNA in distinct stroke subtypes.

Status (registry)
Recruiting
Study type
Observational
Enrollment
200 (estimated)
First submitted
18 Mar 2025
Start date
30 Mar 2025
Primary completion date
1 Sept 2026
Lead sponsor
University Hospital, Basel, Switzerland
Diseases
Stroke
NCT number
NCT06928675

What you commit to

  • Study type: Observational
  • Planned participants: 200
  • From 30 Mar 2025 to the primary completion date, 1 Sept 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients currently undergoing immunological therapies.

Other illness

  • Patients with immunological diseases
  • Patients with systemic infections at the time of admission

Who the study is looking for

  • Acute ischemic stroke due to large vessel occlusion (LVO) who require mechanical thrombectomy (detected in CT-Scan or MRI-Scan)
  • 18 years of age

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
University Hospital Basel
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BaselSwitzerlandRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.