NCT06929091Recruiting
Effect of Prenatal and Postnatal Intervention Strategies on Breastfeeding Outcomes in Women With Excessive Weight (Ready, Set, Nourish Study)
Ready, Set, Nourish Study
Source: ClinicalTrials.gov · Last updated 24 Sept 2026
Brief summary (registry, in English)
This study is about preparing women with excessive weight to have better breastfeeding outcomes. By doing this study, the investigators hope to learn more about how hand expression of breast milk or colostrum during pregnancy can help prepare a mother to breastfeed after she has her baby and about how her diet affects the composition of her breast milk and her baby's growth and development.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 240 (estimated)
- First submitted
- 8 Apr 2025
- Start date
- 7 Nov 2025
- Primary completion date
- 1 Oct 2028
- Lead sponsor
- Arkansas Children's Hospital Research Institute
- Diseases
- Obesity
- NCT number
- NCT06929091
What you commit to
- Study type: Interventional
- Planned participants: 240
- From 7 Nov 2025 to the primary completion date, 1 Oct 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Age 18 or older
- Less than 37 weeks of pregnant with singleton fetus
- Pre-pregnancy excessive weight (Body Mass Index ≥ 25 kg/m2)
- Interested in breastfeeding
- Willing to express colostrum from around 37 weeks of pregnancy if randomized to the prenatal intervention group
- Willing to express human milk for sample collection during a 24-hour period
- Willing to adhere to a meal plan for 5.5 months post-partum if randomized to the postnatal intervention group
- Able to engage in study procedures for the first 24 months postpartum
- Reside in Central Arkansas region Exclusion Criteria
- Pre-existing conditions (e.g. diabetes, hypertension, heart disease, thyroid disorders);
- Use of recreational drugs, tobacco, or 2 or more servings of alcohol per month
- Food allergies, intolerances, or preferences interfering with the meal plan
- Medical history including any contraindication to breastfeeding (medications or supplements incompatible with breastfeeding, substance use)Multiparous pregnancy
- History of breast surgery or radiation
- Congenital defects
- Preeclampsia
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Arkansas Children's Nutrition Center Coordinator of this site? Confirm its status | Little Rock | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.