NCT06929364Recruiting
The Role of Probiotics in the Treatment of Endometriosis (ProMetrioS): a Randomised Double-blinded Placebo-controlled Cross-over Trial
Source: ClinicalTrials.gov · Last updated 16 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
ProMetrioS is a randomised blinded placebo-controlled cross-over trial investigating the effect of specific multistrain probiotics in patients with endometriosis. The aim of this clinical trial is to determine whether probiotic treatment can significantly modulate gut microbiome composition and functionality in endometriosis patients, specifically parameters associated with the estrobolome.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 17 Sept 2024
- Start date
- 1 Nov 2024
- Primary completion date
- 1 May 2025
- Lead sponsor
- The Gut Microbiome Center (Centar za crijevni mikrobiom)
- Diseases
- Endometriosis
- NCT number
- NCT06929364
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Nov 2024 to the primary completion date, 1 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of immunosuppressant, antibiotic, proton pump inhibitors and corticosteroid drugs
- Use of probiotics product less than one month before start of study or during study
Other illness
- Patients with chronic inflammatory diseases (e.g., autoimmune disorders)
Age
- Age \> 35 years
Other
- Immunocompromised patients
- Pregnancy
- Use of supplements and foods with probiotics
Who the study is looking for
- adult subjects with stage III or IV endometriosis diagnosis confirmed by biopsy
Criteria the registry did not label
- Minimum Age: - Maximum Age: 35 Years Sex: Female Gender Based: Ye - only women can participate in this study Accepts Healthy Volunteers: No
Age in the registry: - to 35 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Center Zagreb Coordinator of this site? Confirm its status | Zagreb | Croatia | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.