NCT06930365Completed
Clinical-Instrumental Study To Evaluate And Compare The Efficacy And Tolerability Of Two Emollients Products In Atopic Dermatitis
Clinical-Instrumental Study To Evaluate And Compare The Efficacy And Tolerability Of Two Emollients Products (Investigational Product Versus Placebo) In Atopic Dermatitis
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with erythema, scaly and oozing plaques, and severe pruritus which has an important impact on quality of life and quality of sleep. It is divided into 2 chronic phases : flare-up and remission period. Signs and symptoms of AD are associated with a compromised immune system, a defective skin barrier, a cutaneous dysbiosis and overall inflammatory status. The aim of the study is to evaluate and compare the efficacy and tolerability of two face and body cream products, new emollient versus placebo, in used over the course of 5 weeks as a replacement of usual or any emollient by female and male subjects with atopic dermatitis. This is an interventional, single-center, double-blind, randomized and comparative study.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 64 (actual)
- First submitted
- 24 Feb 2025
- Start date
- 9 Dec 2024
- Primary completion date
- 16 May 2025
- Lead sponsor
- NAOS Les Laboratoires
- Diseases
- Atopic dermatitis (eczema)
- NCT number
- NCT06930365
What you commit to
- Study type: Interventional
- Participants enrolled: 64
- From 9 Dec 2024 to the primary completion date, 16 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pharmacological treatments (topic or systemic) other than topical corticosteroids, known to interfere with skin metabolism / physiology. In particular, no antibiotics taken within 4 weeks preceding the inclusion, nor anti- inflammatories taken within 2 weeks before the inclusion
Other
- Participant does not meet the inclusion criteria,
- Known pregnancy, participant breastfeeding, or not willing to take necessary precautions to avoid a pregnancy during the study,
- Participant with dermatological problems in the test areas other than atopic dermatitis,
- Participant being deprived of liberty by judicial or administrative decision, or under guardianship,
- Participant being linguistically or psychologically incapable of signing informed consent and unable to comply with the protocol requirements,
- Participant who has a relevant change in his state of health since registered in the LTD "Health" Database (change incompatible with inclusion in the study),
- Participant currently enrolled in another similar clinical study or in an exclusion period of a study,
- Participant having a skin recently exposed to sunlight (natural or artificial) and / or having applied a self-tanner on the application areas and /or tanning activator (dietary supplement) within 2 weeks preceding the inclusion.
- Participant having bathed in a swimming pool within 1 week preceding the inclusion or planning to bath in a swimming pool during the study.
Who the study is looking for
- Female and/or male participants,
- Participant aged between 18 years old and more included,
- All ethnicities
- Phototype II to IV
- Participant with all skin types, sensitive or not sensitive,
- 44 subjects having a rash of eczema (SCORAD between 25 and 50) with at least 1 lesional area requiring topical corticosteroid treatment,
- 22 healthy subjects (without any dermatological pathology nor disorder),
- 44 participants having whitened eczema lesions at Dx (between 5 to 10 days) after the topical corticosteroid treatment,
- Participants having signed their written Informed Consent form (ICF) for their participation in the study and a photograph authorization,
- Participant able to comply with the protocol and follow protocol's constraints and specific requirements.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ltd "Health" Coordinator of this site? Confirm its status | Batumi | Georgia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.