NCT06930638RecruitingPhase 2
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes (MITO Study)
Source: ClinicalTrials.gov · Last updated 25 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance. Preliminary data shows a single bout of ischemic conditioning or oral ingestion of an over-the-counter antioxidant supplement called MitoQ may improve vascular function and muscle activity in individuals post-stroke.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 9 Apr 2025
- Start date
- 22 Jul 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Medical College of Wisconsin
- Diseases
- Stroke
- NCT number
- NCT06930638
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 30
- From 22 Jul 2025 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Myocardial infarction or arrhythmia in the previous year
Other illness
- History of blood clots in the extremities or any condition in which compression of the thigh or transient ischemia is contraindicated (i.e., wounds in the leg).
- Chronic lasting symptoms (\> 6 months) of severe COVID-19 (i.e., hospitalization)
- History of head trauma or concussion within the past 6 months
- Comorbid neurological disorder
- Peripheral vascular disease
- Other significant medical condition likely to influence study or jeopardize safety as assessed by the Primary Investigator
Other
- Unable to stand from chair without physical assistance from another person (able to use assistive device).
- Resting SBP ≥180 mmHg or DBP ≥ 100 mmHg
- Pregnant or breastfeeding.
Who the study is looking for
- 18 - 85 years of age
- Cortical or sub-cortical stroke ≥ 6 months ago with residual hemiparesis
- Able to give informed consent and follow 2-step command.
- English Speaking
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical College of Wisconsin Coordinator of this site? Confirm its status | Milwaukee | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.