NCT06931483Enrolling by invitation
The Efficacy and Safety of Transcranial Temporal Interference Stimulation (tTIS) Targeting the Right Globus Pallidus Internus (GPi) for Motor Symptoms in Patients With PD
Source: ClinicalTrials.gov · Last updated 17 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
To demonstrate that intervention targeting the right globus pallidus internus (GPi) using transcranial temporal interference stimulation can improve motor symptoms in patients with Parkinson's disease.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 9 Apr 2025
- Start date
- 1 Sept 2024
- Primary completion date
- 30 Sept 2025
- Lead sponsor
- Yanghua Tian
- Diseases
- Parkinson disease
- NCT number
- NCT06931483
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Sept 2024 to the primary completion date, 30 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous history of TMS or traditional TES treatment;
- Presence of non-MRI compatible metal implants in the body, such as deep brain stimulation devices, pacemakers or stents.
Other illness
- History of other neuropsychiatric disorders;
- History of alcohol or drug abuse;
Who the study is looking for
- Meeting the diagnostic criteria for Parkinson's disease in China (2016 version), diagnosed as PD by two neurologists;
- Hoehn-Yahr stage 1.5-4;
- Age \> 50 years old;
- No signs of moderate to severe depression: Beck Depression Inventory-II (BDI-II) score \< 20;
- No signs of dementia: Mini-Mental State Examination (MMSE) score \> 21;
- No change in medication regimen in the four weeks prior to enrollment;
- Right-handed.
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Anhui Medical University Coordinator of this site? Confirm its status | Hefei | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.