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NCT06931522Completed

Effects of Mat and Reformer Pilates in Multiple Sclerosis

Effects of Mat and Reformer Pilates Training on Postural Adjustments, Balance, and Walking in Patients With Multiple Sclerosis

Source: ClinicalTrials.gov · Last updated 30 Mar 2026

Brief summary (registry, in English)

Our study aims to investigate the effects of core stability-based Mat Pilates and Equipment-Based Pilates training on anticipatory postural adjustments (APA), balance, and gait in individuals with Multiple Sclerosis (MS). Participants diagnosed with MS will be randomly assigned to Mat Pilates, Equipment-Based Pilates, or a control group. Both Pilates programs will be conducted twice a week for eight weeks. Assessments will be conducted before and after the training period. Anticipatory postural adjustments (APA) will be evaluated using electromyography (EMG) electrodes placed on the Erector Spinae and Tibialis Anterior muscles while participants take a step. Biomechanical responses related to APAs, specifically center of pressure displacement, will be measured using a force platform (Biodex® BioSway). Core endurance will be assessed using the lateral bridge test, Modified Biering-Sorensen test, trunk flexion test, and prone bridge test, while core strength will be evaluated through sit-ups and push-ups. Balance will be measured using posturography. The Activities-Specific Balance Confidence (ABC) Scale will assess confidence in performing daily activities requiring balance. Functional mobility will be evaluated using the Timed Up and Go (TUG) test. Spatiotemporal gait parameters and variability will be analyzed with the BTS® G-WALK system. The Multiple Sclerosis Quality of Life Questionnaire (MSQOL-54) will assess quality of life. This study is unique in that, unlike previous Pilates studies, it will be the first to examine the effects of different Pilates methods on APAs, which are crucial for both locomotor activities and postural stability in individuals with MS. Additionally, it will be the first study to evaluate two commonly used Pilates techniques in terms of their impact on balance and gait.

Status (registry)
Completed
Study type
Interventional
Enrollment
30 (actual)
First submitted
21 Mar 2025
Start date
10 Jun 2025
Primary completion date
23 Jan 2026
Lead sponsor
Gazi University
NCT number
NCT06931522

What you commit to

  • Study type: Interventional
  • Participants enrolled: 30
  • From 10 Jun 2025 to the primary completion date, 23 Jan 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Having another neurological disorder
  • Having a disease that may affect the immune system, such as infection, cancer

Other

  • Having orthopedic, cardiovascular, and pulmonary problems that may affect the research results
  • Having vision, hearing, and perception problems

Who the study is looking for

  • Diagnosis of Multiple Sclerosis by a specialist physician
  • Having a disability level between 0-4.5 according to the Expanded Disability Status Scale (EDSS)
  • Being between the ages of 18-65
  • Not having had an attack in the last 3 months
  • Mini-Mental Test score \> 25

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Gazi University
Coordinator of this site? Confirm its status
AnkaraTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.