NCT06931743Recruiting
The Application of Electrical Stimulation in Postoperative Pain Management of Thyroid Surgery
Transcutaneous Electrical Nerve Stimulation Based on Wrist-Ankle Acupuncture Theory for Postoperative Pain After Thyroid Surgery: A Multicenter Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 19 Aug 2026
Brief summary (registry, in English)
Post-thyroidectomy pain is a prevalent early postoperative complication. While pharmacological agents remain the mainstay of analgesia, their clinical application is constrained by adverse effects including nausea, respiratory depression, and gastrointestinal disturbances. Transcutaneous electrical nerve stimulation based on wrist-ankle acupuncture theory (TENS-WAA) is a non-invasive analgesic modality that has demonstrated preliminary benefits in multiple pain scenarios. Nevertheless, robust evidence for its efficacy in post-thyroidectomy pain management is still lacking, limited by single-center designs and small sample sizes in existing studies. This trial aims to evaluate the efficacy and safety of TENS-WAA for pain control after thyroidectomy. The findings are expected to support a standardized non-pharmacological analgesic option as an adjunct to multimodal postoperative pain regimens, aligning with Enhanced Recovery After Surgery (ERAS) principles.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 668 (estimated)
- First submitted
- 17 Mar 2025
- Start date
- 30 Apr 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Xiaonan Huang
- Diseases
- Thyroid cancer
- NCT number
- NCT06931743
What you commit to
- Study type: Interventional
- Planned participants: 668
- From 30 Apr 2025 to the primary completion date, 31 Dec 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Inclusion Criteria:
- Be over 18 years of age;
- The operation time is less than 4 hours;
- Postoperative VAS pain score ≥3 points ;
- Clear consciousness, able to answer questions accurately, free speech, no hearing impairment;
- Informed consent
- Exclusion Criteria:
- Neck or thyroid surgery within the past ten years;
- Menstruating, pregnant and lactating females;Those who are not satisfied with blood glucose control;
- Skin injury or allergy; skin ulceration;
- Past history of psychiatric disorder that met the diagnostic criteria of Diagnostic and Manual of Mental Disorders, DSM-IV;
- Upper respiratory tract infection within 2 weeks before surgery;
- History of implantation of pace or defibrillator;
- Allergic to gel or intolerant to electrical stimulation;
- History of chronic pain, pain VAS score 1 at the examination;
- Use of sedative analgesic drugs for a long time or within 24 hours;
- Particip in other clinical trials in the past 4 weeks.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Changzheng Hospital Affiliated to the Naval Medical University Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
| Changhai Hospital Affiliated to the Naval Medical University Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
| the Specialised Medical Centre of the Chinese People's Liberation Army Navy Coordinator of this site? Confirm its status | Shanghai | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.