NCT06932861RecruitingEarly phase 1
Exploratory Study of Personalized mRNA Vaccine in Patients With Refractory Rhabdomyosarcoma
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
An Exploratory Study on the Use of mRNA Tumor Vaccines in the Treatment of Refractory Rhabdomyosarcoma
- Status (registry)
- Recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 5 (estimated)
- First submitted
- 10 Apr 2025
- Start date
- 13 Oct 2025
- Primary completion date
- 1 May 2027
- Lead sponsor
- Xinxin Zhang
- Diseases
- Childhood cancers, Sarcoma
- NCT number
- NCT06932861
What you commit to
- Study type: Interventional · Early phase 1
- Planned participants: 5
- From 13 Oct 2025 to the primary completion date, 1 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- 1.History of or concurrent with other untreated malignant tumors, except for previously cured basal cell carcinoma of the skin, carcinoma in situ of the cervix, and superficial bladder cancer; 2.History of or current active autoimmune diseases. 3.Has uncontrolled cardiovascular diseases.
Who the study is looking for
- Diagnosed with rhabdomyosarcoma confirmed by pathological or molecular testing;
- Age ≥ 6 years;
- Has residual tumor or minor disease progression following standard therapy, and has no available effective treatment option. (\*: Prior to vaccine administration, during the vaccine manufacturing period, continuation of the prior antitumor regimen is permitted in combination with the study drug(s).)
- Expected survival time greater than 6 months;
- ECOG performance status score of 0-1; -
Age in the registry: 6 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chinese PLA General Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.