NCT06936774RecruitingPhase 3
Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance
Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance - a Randomized Controlled Trial (iRECOVER)
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
The goal of this clinical study is to gain further insights into the treatment of patients with Low Anterior Resection Syndrome (LARS) symptoms after rectal resection. The main question is: Can LARS symptoms and quality of life be improved by implementing an intensified follow-up program? Researchers will compare the results of the intervention group with the results of a control group in which patients do not receive an intensified follow-up program to determine whether the intervention works. Participants will undergo an intensified follow-up program which consists of several follow-up visits and medical treatment, pelvic floor muscle training and gynaecological and urological co-treatment in case of LARS symptoms and urinary or sexual complaints.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 140 (estimated)
- First submitted
- 24 Mar 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 1 May 2028
- Lead sponsor
- University Hospital, Basel, Switzerland
- Diseases
- Colorectal cancer
- NCT number
- NCT06936774
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 140
- From 1 Dec 2025 to the primary completion date, 1 May 2028
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- dementia or other psychiatric disorder that would prevent the patients from answering the questionnaires and experiencing sustainable training effects
Other
- impossibility of stoma reversal due to persistent anastomotic leak and/or local recurrence
Who the study is looking for
- patients older than 18 years
- patients with rectal cancer in the middle and lower third of the rectum in stages I to IV who underwent LAR with TME and protective ileostomy
- able to give informed consent as documented by signature
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clarunis Universitäres Bauchzentrum Basel Coordinator of this site? Confirm its status | Basel | Switzerland | Recruiting |
| Lindenhofspital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Recruiting |
| St. Anna Spital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Not yet recruiting |
| Kantonsspital Luzern Coordinator of this site? Confirm its status | Lucerne | Switzerland | Recruiting |
| Kantonsspital Winterthur Coordinator of this site? Confirm its status | Winterthur | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.