NCT06937164Recruiting
Blood Pressure Following Isometric Exercise in Inactive Adults
Beliefs and Expectation Effects on Blood Pressure Following Isometric Exercise in Inactive Adults
Source: ClinicalTrials.gov · Last updated 16 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed object. Previous research has shown that IET may help reduce blood pressure, but the mechanisms involved are not fully understood. The purpose of this study is to assess both the immediate (acute) and long-term (chronic) effects of IET on cardiovascular outcomes. Participants will complete a series of lab-based exercise sessions over several weeks. In these sessions, they will perform repeated bouts of isometric leg extensions while seated on an exercise machine designed to measure muscle force. Throughout the study, researchers will monitor participants' blood pressure, heart rate, and muscle activity. Acute responses-such as post-exercise hypotension (a short-term drop in blood pressure)-will be measured immediately after exercise. Chronic changes, such as resting blood pressure improvements, will be evaluated across the training period. Additional measurements will include heart rate variability (HRV), which gives insight into autonomic nervous system activity, and electromyography (EMG), which tracks muscle fatigue and activation patterns. These data will help explore potential mechanisms behind the cardiovascular benefits of IET. By examining how repeated sessions of isometric exercise influence blood pressure and related physiological responses, this research may support the use of IET as a non-pharmacological strategy for managing or preventing hypertension in physically inactive individuals.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 36 (estimated)
- First submitted
- 7 Apr 2025
- Start date
- 21 Apr 2025
- Primary completion date
- 30 Aug 2025
- Lead sponsor
- Canterbury Christ Church University
- Diseases
- High blood pressure
- NCT number
- NCT06937164
What you commit to
- Study type: Interventional
- Planned participants: 36
- From 21 Apr 2025 to the primary completion date, 30 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Current diagnosis of hypertension requiring medication
- Any known cardiovascular, neurological, or musculoskeletal condition contraindicating isometric exercise
Other
- Formal education or professional background in exercise science, physiology, or a related field
- Pregnant or planning to become pregnant during the study period
- Inability to follow verbal instructions or complete study protocols
Who the study is looking for
- Age 18 years or older
- Self-reported physically inactive or insufficiently active (not meeting current physical activity guidelines)
- Not currently engaged in structured resistance or isometric exercise training
- Able to attend lab sessions over a 4-week period
- Provides written informed consent
Age in the registry: 18 years to 55 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Canterbury Christ Church University Coordinator of this site? Confirm its status | Canterbury | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.