NCT06938971Recruiting
Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
Effects of Exercise Training on Health-related Quality of Life in Patients With Unresectable Metastatic Colorectal Cancer: A Multi-center Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 31 Mar 2025
- Start date
- 16 May 2025
- Primary completion date
- 1 May 2027
- Lead sponsor
- Copenhagen University Hospital, Rigshospitalet
- Diseases
- Colorectal cancer
- NCT number
- NCT06938971
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 16 May 2025 to the primary completion date, 1 May 2027
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Pregnancy.
- A life expectancy of \< 6 months.
- Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology.
- ECOG (Eastern Cooperative Oncology Group) performance status \> 2.
- Inability to understand the Danish or English language.
- Engagement in structured moderate-to-high aerobic exercise training for \>30 min \>1 times/week for the past 3 months at the time of inclusion.
Who the study is looking for
- \- Adults (≥18 years of age) schduled to undergo first-line chemotherapy for the treatment of metastatic colorectal cancer.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Recruiting |
| Herlev and Gentofte Hospital Coordinator of this site? Confirm its status | Herlev | Denmark | Recruiting |
| North Zealand University Hospital, Hillerød Coordinator of this site? Confirm its status | Hillerød | Denmark | Recruiting |
| Zealand University Hospital, Roskilde Coordinator of this site? Confirm its status | Roskilde | Denmark | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.