NCT06939114Completed
Optic Nerve Sonography to Monitor Intracranial Pressure After Ischemic sTrokE - The ONSITE Study
Source: ClinicalTrials.gov · Last updated 22 Apr 2025
Brief summary (registry, in English)
The goal of the ONSITE study is to investigate whether an increase Optic nerve sheath diameter (ONSD) may help to predict intracranial hypertension (IH) after stroke. IH is a life-threatening complicaitons of malignant middle cerebral artery (MCA) infarction due to space-occupying brain edema. Patients at risk are monitored based on clinical symptoms, which can be difficult due to comorbidities such as delirium or systemic infections, which can hempen clinical judgement. Readily available, non-invasive methods to monitor ICP in stroke patients could help to earlier diagnose rising ICP and facilitate treatment decisions such as hemicraniectomy. This study investigates whether ONSD with optic nerve sonography (ONS) can detect brain edema after stroke.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 107 (actual)
- First submitted
- 4 Apr 2025
- Start date
- 1 Jan 2019
- Primary completion date
- 31 Mar 2024
- Lead sponsor
- University of Zurich
- Diseases
- Stroke, High blood pressure
- NCT number
- NCT06939114
What you commit to
- Study type: Observational
- Participants enrolled: 107
- From 1 Jan 2019 to the primary completion date, 31 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Expected or known non-compliance to participate in the observational study, severe drug- or/and alcohol abuse
Other illness
- Known history of intracranial hypertension
Other
- Known intracranial space-occupying lesion
- Contra-indications on ethical grounds
Who the study is looking for
- ≥ 18 years of age
- Consent according to the regulations of research in an emergency situation
- For non-Control patients: Acute ischemic stroke within 24 hours of recruitment
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Zurich Coordinator of this site? Confirm its status | Zurich | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.