NCT06940687Completed
Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers
Source: ClinicalTrials.gov · Last updated 19 Oct 2026
Brief summary (registry, in English)
This study aims to investigate the neurophysiological effects of live music on individuals with early Alzheimer's Disease (AD), dementia, and/or mild cognitive impairment (MCI) and their caregivers. Heart rate (HR), heart rate variability (HRV), and brain activity will be measured as participant-caregiver dyads listen to preferred and improvised music performed by professional musicians. Investigators will leverage various measurement techniques including, but not limited to, electroencephalography (EEG), behavioral, surveys, and physiological monitoring to study the impact of live music on anxiety in AD and inter-dyad synchrony.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 19 Feb 2025
- Start date
- 28 Jan 2025
- Primary completion date
- 27 Aug 2026
- Lead sponsor
- Yale University
- Diseases
- Alzheimer disease
- NCT number
- NCT06940687
What you commit to
- Study type: Interventional
- Participants enrolled: 10
- From 28 Jan 2025 to the primary completion date, 27 Aug 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Starting a new prescription medication in the last 6 months
Other illness
- Clinical Dementia Rating \<0.5 or \> 2
- Participating in another clinical trial studying AD and/or Dementia
Other
- Unable to provide informed consent
- Endorsing suicidal ideation (SI), self-injurious behavior, or homicidal ideation (HI) above the threshold defined in the "Risk Reduction and Safety Plan"
- Prescribed Benzodiazepines on an as needed basis
Who the study is looking for
- Clinical Dementia Rating 0.5 - 2
- Be a person with or caregiver to a person with a diagnosis of early Alzheimer's Disease, mild dementia, and/or mild cognitive impairment (MCI)
- Able to provide informed consent
- Willing to wear an EEG headset and heart rate monitoring devices
- Willing to possibly have small patches of body / facial hair shaved to accommodate administration of heart rate monitoring devices
- Willing to answer survey questions about topics related to the study
- Willing to be audio / video recorded
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Firehouse 12 Studios Coordinator of this site? Confirm its status | New Haven | United States | Unknown status |
| Musical Intervention Studios Coordinator of this site? Confirm its status | New Haven | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.