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NCT06941168Completed

Potential Advantages of Robotic Total Gastrectomy in Advanced Middle-Upper Gastric Cancer: A Multicenter Propensity Score Matching Analysis

Potential Advantages of Robotic Total Gastrectomy in Advanced Middle-Upper Gastric Cancer

Source: ClinicalTrials.gov · Last updated 23 Apr 2025

Brief summary (registry, in English)

This multicenter retrospective cohort study aimed to evaluate the potential advantages of robotic total gastrectomy (RTG) compared to laparoscopic total gastrectomy (LTG) in patients with advanced middle and upper gastric cancer (AMUGC). A total of 1,099 patients who underwent radical total gastrectomy between 2013 and 2020 were included. After strict inclusion and exclusion criteria, propensity score matching (1:1) was conducted to balance baseline characteristics. The primary endpoint was 3-year disease-free survival (DFS), with secondary outcomes including overall survival, recurrence rates and patterns, and perioperative outcomes. All procedures were performed by experienced surgeons following standardized protocols across eight high-volume centers. Data quality was ensured through a centralized electronic system, unified training, and rigorous verification. This study provides real-world evidence on surgical outcomes and long-term prognosis, contributing to clinical decision-making in the treatment of AMUGC.

Status (registry)
Completed
Study type
Observational
Enrollment
1099 (actual)
First submitted
16 Apr 2025
Start date
Jan 2015
Primary completion date
Jun 2019
Lead sponsor
Fujian Medical University
NCT number
NCT06941168

What you commit to

  • Study type: Observational
  • Participants enrolled: 1099
  • From Jan 2015 to the primary completion date, Jun 2019
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Use of indocyanine green (ICG) during surgery
  • Received neoadjuvant chemotherapy
  • Combined resection of other organs

Other illness

  • Residual gastric cancer
  • History of concurrent or previous malignancies

Other

  • \- American Society of Anesthesiologists (ASA) class \> 3
  • Lost to follow-up

Who the study is looking for

  • \- Diagnosed with middle or upper gastric cancer (GC)
  • Pathological stage T2-T4a, N0-N3b, M0 (postoperative)
  • Underwent radical total gastrectomy

Age in the registry: 20 years to 85 years · Sex: All

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Department of Gastric Surgery, Fujian Medical University Union Hospital
Coordinator of this site? Confirm its status
FuzhouChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.