NCT06941779Completed
CuePD: Investigating the Effect of Personalised Auditory Cueing on Gait in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 29 Apr 2026
Brief summary (registry, in English)
Parkinson's Disease (PD) is a major cause of disability, globally. PD affects a person's movement speed, fluency, quality, and ease of walking. PD has the fastest-growing incidence rate, with its prevalence expected to double over the next three decades, currently affecting 10 million people worldwide. PD often leads to disturbances in walking/gait characteristics such as abnormal/variable stride lengths and step times. Those disturbances increase the risk of falls, with about 39% of people with PD (PwPD) experiencing an average of 20.8 falls/year. Research has examined cueing by leveraging auditory, visual, and tactile cues to normalize variable gait characteristics and improve mobility to reduce falls. Auditory cueing is the most effective at improving gait and most practical to apply in all settings (via headphones) but one size does not fit all when using auditory cueing paradigms i.e., there is a need for personalised approaches to ensure cueing interventions are tailored to the individual and their specific functional limitations. Furthermore, the long-term effectiveness of auditory mechanisms (e.g., metronome-based repetitive beep) suffer from their lack of continuous engagement. This research project aims to examine personalised auditory cueing to improve gait in PwPD. Inertial sensors will capture and analyze validated gait-related characteristics and personalised auditory cues will be examined for their ability to correct variable gait. To reduce burden on PwPD (i.e., minimal number of wearable sensors) and to streamline data capture and deliver auditory cues, a single smartphone will be used only. The project involves a multidisciplinary study between Computing and Exercise and Rehabilitation at Northumbria University, testing cueing modalities in a controlled laboratory environment under trained researcher supervision. The study will enrol PwPD, focusing on the ability of personalised auditory cueing to improve gait and PwPD preference of auditory cues.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 31 Mar 2025
- Start date
- 21 Nov 2024
- Primary completion date
- 19 Mar 2026
- Lead sponsor
- Northumbria University
- Diseases
- Parkinson disease
- NCT number
- NCT06941779
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 21 Nov 2024 to the primary completion date, 19 Mar 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of stroke, traumatic brain injury or other neurological disorders (other than PD)
- Acute lower back or lower extremity pain, peripheral neuropathy, and musculoskeletal disorders that would affect tasks.
- Unstable medical condition including cardio-vascular instability in the past 6 months
Other
- Non-English speakers
- Unable to comply with the testing protocol or currently participating in another interfering research project
Who the study is looking for
- Able to walk unaided.
- Diagnosis of idiopathic PD, as defined by the UK Brain Bank criteria.
- Score ≥21/30 on Montreal Cognitive Assessment (MoCA) which is used to classify non-demented PD (PD dementia is \<21/30).
Age in the registry: 50 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northumbria University Coordinator of this site? Confirm its status | Newcastle | United Kingdom | Unknown status |
| North Tyneside General Hospital Coordinator of this site? Confirm its status | North Shields | United Kingdom | Unknown status |
Related publications
- Retraining gait in Parkinson's Disease via a personalised app: A study protocol.PLoS One · 2026 · PMID 41984908
This page is information, not medical advice. Discuss any trial with your doctor.