NCT06941961Recruiting
iTBS for Acute Ischemic Stroke After Thrombectomy
Efficacy and Safety of Intermittent Theta Burst Stimulation in Acute Anterior Circulation Ischemic Stroke Patients Undergoing Mechanical Thrombectomy
Source: ClinicalTrials.gov · Last updated 30 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this randomized, single-blind, parallel-controlled clinical trial is to evaluate the efficacy and safety of intermittent theta burst stimulation (iTBS) as an adjunctive therapy for acute anterior circulation ischemic stroke patients who have undergone successful mechanical thrombectomy (MT). The study population includes adults aged 18-85 with NIHSS scores 5-25 post-MT and eTICI≥2b reperfusion.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 178 (estimated)
- First submitted
- 15 Apr 2025
- Start date
- 25 Apr 2025
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Yi Yang
- Diseases
- Stroke
- NCT number
- NCT06941961
What you commit to
- Study type: Interventional
- Planned participants: 178
- From 25 Apr 2025 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- 1\) Pre-stroke modified Rankin Scale (mRS) score ≥2.
- 2\) PH2-type intracranial hemorrhage on brain CT post-MT.
- 4\) Contraindications to iTBS: History of epilepsy or seizures, implanted cardiac pacemakers, cochlear implants, or other electronic/magnetic-sensitive devices.
- 5\) Severe consciousness impairment, cognitive dysfunction, or psychiatric disorders preventing compliance with iTBS.
- 6\) Expected survival \<3 months due to other medical conditions or inability to complete follow-up for any reason.
- 8\) Any other condition deemed unsuitable for enrollment by the investigator.
Other
- 3\) Patients who underwent intracranial stent placement during MT.
- 7\) Participation in another interventional study.
Who the study is looking for
- 1\) Age 18-85 years, regardless of gender.
- 2\) Acute ischemic stroke caused by occlusion of the anterior circulation large vessels (internal carotid artery, M1 or M2 segment of the middle cerebral artery), verified by CTA or DSA.
- 3\) Mechanical thrombectomy (MT) performed within 24 hours of symptom onset.
- 4\) Successful Reperfusion: Post-MT eTICI score ≥ 2b.
- 5\) NIHSS score 5-25 at 24 hours post-MT, with ≥2 points in at least one limb.
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Hospital of Jilin University Coordinator of this site? Confirm its status | Changchun | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.