NCT06944353Enrolling by invitation
Improving Diagnostic Safety Through STeatosis Identification, Risk Stratification, and Referral in the ED
Improving Diagnostic Safety Through STeatosis Identification, Risk Stratification, and Referral in the ED (STIRRED)
Source: ClinicalTrials.gov · Last updated 29 May 2026
Brief summary (registry, in English)
Hepatic steatosis is a common radiographic "incidental finding" that is overlooked and underreported to patients. The investigators developed a clinical decision support system using machine learning and natural language processing that will prompt reporting to patients and provide ED clinicians risk stratified follow-up care recommendations. Data on both the implementation and effectiveness of our intervention resulting from this trial will inform future use with a goal of ultimately improving diagnostic safety and outcomes for patients with hepatic steatosis.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 4704 (estimated)
- First submitted
- 16 Apr 2025
- Start date
- 4 Dec 2025
- Primary completion date
- Jan 2027
- Lead sponsor
- Northwestern University
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT06944353
What you commit to
- Study type: Interventional
- Planned participants: 4704
- From 4 Dec 2025 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- pre-existing Liver Disease diagnosis (Liver Cancer, HCV, HBV, Cirrhosis, NAFLD/MASLD/NASH/MASH, Alcohol Liver Disease, PSC, PBC and autoimmune hepatitis)
Age
- age \< 18
Other
- admitted to the hospital
Who the study is looking for
- imaging finding of hepatic steatosis on ED imaging study
- discharged from the ED to home
- first Northwestern Medicine ED visit in the study period with a hepatic steatosis finding
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwestern Memorial Hospital Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.