NCT06945094Not yet recruiting
A Multi-center, Real-World Clinical Trial of caIMR on Two Specific Kinds of Patients.
A Multi-center, Real-World Clinical Trial on Assessment of Microcirculatory Status Using Online Coronary Angiography-Derived Index of Microcirculatory Resistance (caIMR) (Flash V)
Source: ClinicalTrials.gov · Last updated 27 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The coronary angiography-derived index of microcirculatory resistance (caIMR) can be used to provide a binary assessment whether patients（with stable angina, unstable angina, suspected myocardial ischemia, or coronary artery stenosis of less than 50%, and without cardiomyopathy or obstructive epicardial coronary artery disease） have microcirculatory dysfunction, using a cutoff value of 25. This study aims to evaluate the binary classification performance of caIMR in two specific groups of patients: (1) those with caIMR values between 20 and 30, and (2) those with diffuse disease. We will do this by looking at differences in their Seattle Angina Questionnaire (SAQ) scores and their health outcomes over a three-year period.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 508 (estimated)
- First submitted
- 18 Apr 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 30 Dec 2027
- Lead sponsor
- Ge Junbo
- Diseases
- Coronary artery disease
- NCT number
- NCT06945094
What you commit to
- Study type: Observational
- Planned participants: 508
- From 1 Jul 2025 to the primary completion date, 30 Dec 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previously undergone percutaneous coronary intervention (PCI);
- Patients who are currently participating in other clinical trials involving drugs or devices and have not yet reached the primary endpoint of those trials;
Other illness
- History of heart failure or myocardial infarction;
- Acute myocardial infarction;
- Primary or secondary severe valvular heart disease;
- Severe systemic infections;
- Malignant cachectic diseases and an estimated survival of less than one year;
- Patients whom the investigator deems to have other conditions that make them unsuitable for participation in the clinical trial.
Other
- Primary or secondary cardiomyopathy;
Who the study is looking for
- Age between 18 and 80 years, regardless of gender;
- Diagnosed with stable angina, unstable angina, or suspected myocardial ischemia;
- targeted vessel stenosis \< 50% and caIMR values between 20 and 30; or
- (3) Targeted vessel stenosis \< 50%, but with lesion length \> 20 mm and caFFR \> 0.8, representing diffuse disease.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.