NCT06948058Recruiting
Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy
Source: ClinicalTrials.gov · Last updated 18 May 2026
Brief summary (registry, in English)
This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 22 Apr 2025
- Start date
- 1 Apr 2025
- Primary completion date
- 31 May 2027
- Lead sponsor
- Brown University
- Diseases
- Obesity
- NCT number
- NCT06948058
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Apr 2025 to the primary completion date, 31 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- received smoking cessation treatment of any kind in the past 30 days (actively quitting smoking),
- currently using EC or NRT more than 2 days/week (this may affect responses to study-supplied products)
- taken prescription weight loss medication in the last 30 days
Other illness
- hospitalized for mental illness in past 30 days
- heart-related event (e.g., heart attack, severe angina) in past 30 days
- medical contraindication for study or product use (e.g., allergy to adhesives)
Other
- residing with another person currently enrolled in the study
- pregnant, nursing, or planning to become pregnant in the next 6 months
Who the study is looking for
- body mass index (BMI) ≥ 30 kg/m2 (i.e., obese)
- smoked ≥ 5 cigarettes/day during the past year
- 21 or older (due to minimum legal age EC restrictions)
- exhaled breath carbon monoxide (CO) level \> 6 ppm at Baseline (BL) (to confirm self-reported smoking)
- willing to use EC or NRT for 8 weeks
- access to a Bluetooth-enabled smartphone/tablet (to permit remote measurement of CO and other outcome variables)
Age in the registry: 21 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brown University Coordinator of this site? Confirm its status | Providence | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.