NCT06949774Recruiting
INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND)
INcentives and ReMINDers to Improve Long-term Medication Adherence
Source: ClinicalTrials.gov · Last updated 14 Jul 2026
Brief summary (registry, in English)
Low medication adherence when initiating antiretroviral treatment (ART) is a key barrier to HIV virologic suppression, resulting in avoidable cases of drug resistance, death, and viral transmission. Routinized pill-taking can lead to successful long-term ART adherence, and short-term behavioral economics-based supports are a novel way to overcome the limited success of existing routinization interventions. This study proposes to test this combined approach for promoting long-term ART adherence using a Stage III Sequential, Multiple Assignment, Randomized Trial (SMART) design in one of the largest HIV clinics in Uganda to identify the most cost-effective adaptive intervention that if found effective is generalizable to other settings and other chronic diseases.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 550 (estimated)
- First submitted
- 22 Apr 2025
- Start date
- 2 Apr 2025
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- RAND
- Diseases
- HIV
- NCT number
- NCT06949774
What you commit to
- Study type: Interventional
- Planned participants: 550
- From 2 Apr 2025 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Not mentally fit to consent.
- Language other than Luganda or English.
- Not willing to consistently use the Wisepill device for adherence measurement.
Who the study is looking for
- Male and female clients age 18 and older.
- Started ART at Mildmay or another clinic within the preceding 2 months
- Able to speak and understand either English or Luganda.
- Have their own cell phone or have consistent access to someone else's phone.
- Willing to receive daily text messages for the 6 months of intervention duration.
- Willing and able to use the WisePill device distributed for adherence verification for the duration of the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mildmay Uganda Coordinator of this site? Confirm its status | Kampala | Uganda | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.