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NCT06951074RecruitingPhase 2/3

Insulin Producing Stem Cell Transplantation Clinical Trial in Type 1 Diabetes

Autologous Insulin Producing Mesenchymal Stem Cell Transplantation in Youth With Type 1 Diabetes

Source: ClinicalTrials.gov · Last updated 30 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Type 1 Diabetes is a chronic autoimmune disease. It results from autoimmune destruction of pancreatic Beta cells leading to absolute insulin insufficiency. The establishment of pluripotent like human stem cells derived from adipose tissue derived mesenchymal cell origin have introduced a new potential source for cell therapy in type 1 diabetic patients, especially in light of recent successes in producing glucose-sensitive insulin secreting cells and this will be the scope of this study. In the last decade, human clinical trials of introducing insulin producing stem cells from various origins were approved and conducted.

Status (registry)
Recruiting
Phase (registry)
Phase 2/3
Study type
Interventional
Enrollment
20 (estimated)
First submitted
4 Apr 2025
Start date
1 Apr 2025
Primary completion date
1 May 2026
Lead sponsor
Ain Shams University
NCT number
NCT06951074

What you commit to

  • Study type: Interventional · Phase 2/3
  • Planned participants: 20
  • From 1 Apr 2025 to the primary completion date, 1 May 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • patients with other autoimmune diseases
  • patients with other chronic diseases

Other

  • patients with micro or macro vascular complications

Who the study is looking for

  • Type 1 diabetes

Age in the registry: 15 years to 18 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Children Hospital Eldemerdash
Coordinator of this site? Confirm its status
CairoEgyptRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.