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NCT06951100Recruiting

Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation

Source: ClinicalTrials.gov · Last updated 26 Oct 2026

Brief summary (registry, in English)

The goal of this observational study is to better understand the role of measuring troponin (a protein measured by a blood test) and coronary imaging in patients presenting with rapid atrial fibrillation (AF) The main questions this study aims to answer are: 1. Are patients with a fast, irregular heartbeat (rapid AF) and damage to the heart (myocardial injury) more likely than those without damage to the heart to have blocked heart arteries (obstructive coronary artery disease) 2. Are patients with a fast, irregular heartbeat (rapid AF) and damage to the heart (myocardial injury) with further evidence that their heart hasn't been getting enough oxygen (myocardial ischemia) more likely to have imaging evidence of myocardial infarction than those without myocardial ischemia To do this, we will measure troponin in patients with rapid AF and then carry out further investigations of the heart (electrocardiogram, echocardiogram, CT scan and cardiac MRI)

Status (registry)
Recruiting
Study type
Observational
Enrollment
300 (estimated)
First submitted
28 Apr 2025
Start date
1 May 2025
Primary completion date
Dec 2026
Lead sponsor
University of Edinburgh
NCT number
NCT06951100

What you commit to

  • Study type: Observational
  • Planned participants: 300
  • From 1 May 2025 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous myocardial infarction
  • Previous coronary revascularisation procedure
  • Previous enrolment in the trial

Lab values

  • Patients in renal failure (eGFR \<30ml/min/1.73m2) or major allergy to contrast media

Other

  • Pregnancy or breast feeding
  • Deemed unsuitable for participation in the study by the attending clinician

Who the study is looking for

  • Age 18 years and over
  • Primary presentation with symptoms related to atrial fibrillation
  • Atrial fibrillation with a ventricular rate \>100 bpm on a 12-lead electrocardiogram
  • Able to provide informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Royal Infirmary of Edinburgh
Coordinator of this site? Confirm its status
EdinburghUnited KingdomRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.