NCT06951802RecruitingPhase 4
Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine
Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine A Single-Centre, Prospective, Randomized, Controlled Trial
Source: ClinicalTrials.gov · Last updated 30 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
RCT comparing intraoperative administration of low-dose ketamine during laparoscopic endometriosis operation and the postoperative pain outcome
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 118 (estimated)
- First submitted
- 16 Apr 2025
- Start date
- 3 Dec 2024
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- Insel Gruppe AG, University Hospital Bern
- Diseases
- Endometriosis
- NCT number
- NCT06951802
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 118
- From 3 Dec 2024 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Myocardial infarction during the last 30 days prior to surgery
Other illness
- Liver disease
- Known malignant hyperthermia
- Cardiovascular instability or severe heart failure (New York Heart Association classification (NYHA) \> III)
- Limited peripheral autonomic activity, hypersensitivity to ketamine or propofol or its components
Age
- Age \< 18 years
Other
- ASA physical status ≥4
- Higher-grade atrioventricular block without pacemaker
- Severe hypovolemia or bradycardia
- Uncontrolled hyper- or hypotension
- Increased intracranial or increased intraocular pressure
- Pregnancy
- Rejection or lack of consent of the patient or relatives
Who the study is looking for
- Patients undergoing surgery for endometriosis operation requiring general anaesthesia at the Inselspital, Bern University Hospital, University of Bern, Department of gynaecology and obstetrics.
- Age ≥ 18 years
- American Society of Anesthesiologist (ASA) physical status 1-3
- Patients with known or suspected endometriosis
- Written informed consent.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Inselspital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Recruiting |
Related publications
- Opioid-sparing by low-dose ketamine for endometriosis surgery. A single-center, prospective, randomized, trial.Pain Manag · 2026 · PMID 41550074
This page is information, not medical advice. Discuss any trial with your doctor.