NCT06953609Completed
Prediabetes and Type 2 Diabetes in Aging
Effects of Prediabetes and Type 2 Diabetes on Cognitive Status, Physical Function, and Fatigue in Geriatric Individuals: A Case-Control Study
Source: ClinicalTrials.gov · Last updated 19 Sept 2025
Brief summary (registry, in English)
This case-control study will evaluate the effects of geriatric individuals on cognitive status, physical function and fatigue. Our study aims to compare the effects of geriatric individuals with prediabetes and type 2 diabetes with healthy geriatric individuals on cognitive status, physical function and fatigue. Accordingly, the hypotheses of the study are as follows: Hypothesis 1: Prediabetes and Type 2 Diabetes Negatively Affect Cognitive Status in Geriatric Individuals. Hypothesis 2: Physical Function Loss is More Pronounced in Individuals with Prediabetes and Type 2 Diabetes. Hypothesis 3: Fatigue Level Will Increase in Geriatric Individuals with Prediabetes and Type 2 Diabetes. Hypothesis 4: There Will Be a Correlation Between the Effects of Prediabetes and Type 2 Diabetes on Cognitive Status, Physical Function and Fatigue. Hypothesis 5: Severity of Diabetes (Prediabetes vs. Type 2 Diabetes) Will Create Differences in Cognitive, Physical and Fatigue Status. Prediabetic, diabetic and healthy volunteers constitute the universe of the study. There will be 4 different groups in the study. These groups are; those with normal range of Hemoglobin A1c Levels (HbA1c) between 4% and 5.6% for people without diabetes (Healthy), those with HbA1c level between 5.7% and 6.4%, those with prediabetes (Impaired Glucose Tolerance), those with 6.5% - 7.5% and those with HbA1c level above 7.5. Cognitive status, physical functions, dual task performance, motor motor and motor cognitive performances, fatigue, reaction reactions, directional skills of elderly individuals will be compared between these groups.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 94 (actual)
- First submitted
- 19 Apr 2025
- Start date
- 15 Apr 2025
- Primary completion date
- 15 Aug 2025
- Lead sponsor
- Uşak University
- Diseases
- Type 2 diabetes
- NCT number
- NCT06953609
What you commit to
- Study type: Observational
- Participants enrolled: 94
- From 15 Apr 2025 to the primary completion date, 15 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- those using any neurological or psychological medication (anticonvulsant drugs, antidepressants, anxiolytics, etc.),
Other illness
- uncontrolled thyroid disease,
- those with uncontrolled hypertension,
- those with any neuropsychological disorder, a history of alcohol, substance or drug addiction,
- those with Alzheimer's and Parkinson's disease,
- those with cancer,
- those with lung disease
Other
- those who have major depression,
- those with vitamin B12, folic acid deficiency and anemia,
- those with nephropathy and retrophy,
Who the study is looking for
- for people without diabetes (healthy), those with Hemoglobin A1c Levels (HbA1c) normal range between 4% and 5.6%,
- those with HbA1c level between 5.7% and 6.4%, those with prediabetes (Impaired Glucose Tolerance),
- those with 6.5% -7.5% level and
- those with HbA1c level above 7.5
- criteria are being 60 years of age and older,
Age in the registry: 60 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Uşak Education and Research Hospital Coordinator of this site? Confirm its status | Uşak | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.