NCT06957626Recruiting
Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy
Source: ClinicalTrials.gov · Last updated 1 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The characteristics of the intestinal microbiota in high-risk colorectal polyp recurrence and their relationship with disease pathogenesis have not yet been fully elucidated. This study aims to analyze the microbial community characteristics in the intestinal mucosal tissue of patients after polypectomy with recurrence of colorectal polyps. Additionally, this research holds significant importance for understanding the etiology of adenoma recurrence and develop a microbiota and metabolite-based predicting tool.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 26 Apr 2025
- Start date
- 25 Apr 2023
- Primary completion date
- 30 Apr 2026
- Lead sponsor
- Peking Union Medical College Hospital
- Diseases
- Colorectal cancer
- NCT number
- NCT06957626
What you commit to
- Study type: Observational
- Planned participants: 150
- From 25 Apr 2023 to the primary completion date, 30 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- patient with previous surgical procedures on the gastrointestinal tract,
- within 1 month before enrollment, oral antibiotics and probiotics were taken;
Other illness
- patient with severe physical diseases that prevented them from adhering to the examination requirements,
- presence of colorectal cancer or other malignant tumor at baseline
- presence of inflammatory bowel disease or hereditary polyposis syndromes (such as family adenomatous polyposis or Lynch syndrome)
Other
- patient with coagulopathy or other contraindications for biopsy or polypectomy,
- inability to provide informed consent or refusal to participate in the study.
Who the study is looking for
- patients aged 40-75 years who undergo the colonoscopy with at least 1 advanced premalignant polyps or ≥ 3 adenoma
Age in the registry: 40 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Peking Union Medical College Hospital, 1 Shuaifuyuan, Dongcheng District, Beijing, China Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.