NCT06960057Completed
Virtual Reality as a Tool to Lower Blood Pressure and Anxiety in Clinic Settings
Exploring Virtual Reality as a Clinical Tool for Blood Pressure Reduction and Assessment of White Coat Hypertension/Effect: A Pre- and Post-Intervention Study With ABPM Validation
Source: ClinicalTrials.gov · Last updated 5 Nov 2025
Brief summary (registry, in English)
This clinical trial aims to evaluate whether a calming virtual reality (VR) experience can reduce office blood pressure (OBP) and anxiety in adults undergoing ambulatory blood pressure monitoring (ABPM) at Mayo Clinic in Florida. The main questions it aims to answer are: 1. Does a 5-minute calming VR session reduce office blood pressure in patients with suspected white coat hypertension or white coat effect? 2. Does VR exposure reduce self-reported anxiety levels in the clinical setting? 3. Does VR reduce the difference between home (ABPM) and clinic blood pressure readings? Participants will: 1. Complete two short electronic surveys (before and after VR exposure) on a clinic-provided device. 2. Undergo a 5-minute virtual reality (VR) relaxation session. 3. Have their blood pressure measured before and after the VR session. Participation will occur during the participant's scheduled ABPM device return visit and will add approximately 30 minutes to the visit. This is a single-arm, pre-post interventional study where each participant serves as their own control.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 79 (actual)
- First submitted
- 21 Apr 2025
- Start date
- 2 Jun 2025
- Primary completion date
- 15 Aug 2025
- Lead sponsor
- Mayo Clinic
- Diseases
- High blood pressure
- NCT number
- NCT06960057
What you commit to
- Study type: Interventional
- Participants enrolled: 79
- From 2 Jun 2025 to the primary completion date, 15 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of epilepsy or seizure disorders.
- Significant cognitive impairment (e.g., dementia, Alzheimer's disease).
- Significant visual impairment that prevents visualization of the VR environment.
- History of vestibular disorders (e.g., Meniere's disease, chronic vertigo).
- Unstable cardiovascular conditions (e.g., myocardial infarction within the past year).
- Chronic hypoxemic respiratory failure requiring supplemental oxygen.
Other
- Cervical spine instability or injuries that could impair safe VR use.
- Current pregnancy
Who the study is looking for
- Age 18 years or older.
- Undergoing ambulatory blood pressure monitoring (ABPM) at Mayo Clinic Florida for any clinical indication.
- Able and willing to provide informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic Florida Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
Related publications
- Virtual Reality Reduces Office Blood Pressure and Anxiety in Patients Undergoing Ambulatory Blood Pressure Monitoring: Enhanced Response among Those With a Pronounced White Coat Response.J Clin Hypertens (Greenwich) · 2026 · PMID 42723367
This page is information, not medical advice. Discuss any trial with your doctor.