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NCT06960304Recruiting

Effect of a Structured Physical Exercise Program on Arteriovenous Fistula Maturation for Hemodialysis in Chronic Kidney Disease Patients

Source: ClinicalTrials.gov · Last updated 8 Jul 2026

Brief summary (registry, in English)

For patients living with Chronic Kidney Disease who are preparing to start hemodialysis, having a well-functioning arteriovenous fistula (AVF) is essential. Although the AVF is considered the best type of vascular access, its maturation process does not always go as expected-studies show that in 28% to 53% of cases, the fistula does not mature properly, making effective dialysis more difficult. There is growing interest in using physical exercise as a way to support AVF maturation. International guidelines even recommend arm exercises for this purpose. However, there is still no clear agreement on what type of exercise, how often, or how intense it should be. This study aims to evaluate whether a structured exercise program focused on the AVF arm can help improve the fistula's development and overall function.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
128 (estimated)
First submitted
15 Apr 2025
Start date
16 Jan 2025
Primary completion date
31 Dec 2027
Lead sponsor
Unidade Local de Saúde de Coimbra, EPE
NCT number
NCT06960304

What you commit to

  • Study type: Interventional
  • Planned participants: 128
  • From 16 Jan 2025 to the primary completion date, 31 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • History of previous dysfunctional ipsilateral AVF

Other illness

  • History of injury/condition causing pain or loss of function in the AVF limb
  • Musculoskeletal conditions/osteoarticular pathology (e.g., myopathy, rheumatoid arthritis)
  • Neurological conditions/cardiovascular events (e.g., stroke, peripheral neuropathy

Who the study is looking for

  • Age ≥ 18 years
  • AVF in the upper limb
  • No cognitive decline and ability to follow instructions

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Unidade Local de Saude de Coimbra
Coordinator of this site? Confirm its status
CoimbraPortugalRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.