NCT06961149Recruiting
Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate
Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate: a Prospective , Randomized Controlled, Non-inferiority Study
Source: ClinicalTrials.gov · Last updated 7 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long withdrawal time of the endoscope and the resulting increase in time and cost. Linked-color imaging (LCI) is a newly developed image-enhanced endoscopy technology. It relies on wave length optimization of three colors (red, green, and blue) to make the lesions appear fuller. LCI improves the visibility of colorectal adenomas and polyps and may increase the detection rate of lesions. In order to explore the clinical application value of Linked-color imaging endoscopy, we performed a prospective, randomized controlled trial to compare adenoma detection rate of Linked-color imaging endoscopy and indigo carmine chromoendoscopy.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 352 (estimated)
- First submitted
- 20 Apr 2025
- Start date
- 8 Apr 2025
- Primary completion date
- 31 Jan 2026
- Lead sponsor
- Shandong University
- Diseases
- Colorectal cancer
- NCT number
- NCT06961149
What you commit to
- Study type: Interventional
- Planned participants: 352
- From 8 Apr 2025 to the primary completion date, 31 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with aspirin, clopidogrel or other anticoagulants/ antiplatelet drugs intake within 7 days
- Patents previous colorectal resection
Other illness
- Patients with pregnancy, inflammatory bowel disease, familial adenomatosis polyposis, suspected CRC; intestinal obstruction, coagulopathy
Other
- Patients with failed cecal intubation
- Patients with inadequate bowel preparation quality (BBPS≤5)
- Patients who refuse to participate or to provide informed consent
Who the study is looking for
- Age between 45 and 85 years
- Patients with a history of colorectal adenoma
- Patients whose first-degree relatives have a history of colorectal cancer or colorectal adenoma
- Patients with gastrointestinal symptoms (abdominal pain, bloody stool, chronic diarrhea or constipation, Unexplained anemia or weight loss;
- Patients with positive Fecal Immunochemical Test
Age in the registry: 45 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Qilu Hospital of Shandong University Coordinator of this site? Confirm its status | Jinan | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.