NCT06961851CompletedEarly phase 1
Feasibility Pilot of Accelerated Stimulation With TMS for Treatment of Major Depressive Disorder (FAST-MDD)
Source: ClinicalTrials.gov · Last updated 9 Feb 2026
Brief summary (registry, in English)
This is a mixed-methods study that includes three steps. The first is a focus group to collect opinions and feedback about implementation of aTMS among clinicians, technicians, nurses, and other clinical staff at the St. Louis Park (SLP) clinic who are experienced with delivering TMS. The second is the delivery of a set of questionnaires delivered to TMS patients at the SLP clinic who are awaiting the start of their TMS series. The third is the delivery of aTMS utilizing the MagVenture TMS device to patients on the SLP rTMS waitlist. The purpose of this feasibility study is to examine the acceptability and efficacy of Accelerated Transcranial Magnetic Stimulation (aTMS) delivered using an accelerated schedule. Repetitive Transcranial Magnetic Stimulation (rTMS) is traditionally delivered once a day, five days a week, for nearly 7 weeks for a total of 36 treatments. While aTMS is quick to deliver, a standard session lasting 10-20 minutes, this schedule is time intensive for patients. It often requires time off from work to accommodate daily driving time to and from the clinic as well as treatment time. This can be disruptive to a patients life and ability to attend all treatment sessions while continuing with their own life responsibilities.
- Status (registry)
- Completed
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 11 (actual)
- First submitted
- 29 Apr 2025
- Start date
- 9 Jun 2025
- Primary completion date
- 1 Feb 2026
- Lead sponsor
- University of Minnesota
- Diseases
- Depression
- NCT number
- NCT06961851
What you commit to
- Study type: Interventional · Early phase 1
- Participants enrolled: 11
- From 9 Jun 2025 to the primary completion date, 1 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Has received TMS in the last 3 months
Other illness
- Presence of any contraindication to TMS assessed by the TMS Adult Safety Screen including individual history of uncontrolled seizures
- Current or history of alcohol abuse
Other
- Diagnosis of Bipolar Depression
- Any lifetime psychosis or mania
- Recent suicide attempt within 90 days of study visit
- Use of Benzodiazepines in past 4 weeks
Who the study is looking for
- Age between 18 and 70 years old
- Current patient of SLP Clinic
- Diagnosis of Unipolar Depression
- Have tried at least 1 antidepressant
- Ability to maintain stable medication regimen for duration of study
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Minnesota Coordinator of this site? Confirm its status | Minneapolis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.